The 5,300-year-old ice mummy known as "Ötzi" who was discovered in 1991 in a receding glacier in the Alps between Italy and Austria, appears to have had the oldest known case of Lyme disease.
When analyzing the Iceman's genome, scientists found genetic material from the bacterium responsible for the disease which is spread by ticks and causes a rash and flulike symptoms, and which can lead to joint, heart and nervous system problems.
The good news for modern Lyme disease sufferers is that this is an infection that is relatively hard to get and easy to treat. I supposed I am living proof of that, as I spent a lot of time in the yard and in the field, routinely get ticks on me, and have never come down with the slightest problem. Ditto for the dogs.
I have written on Lyme disease in the past, detailing the billion dollar veterinary scam that involves tests and vaccines, and providing links to a veterinary consensus paper (PDF) on the same.
Because I stocked up on Doxycyline some time back (500 100 mg doses) my antibiotics needs for Lyme and Hearworm are probably taken care of for life (antibiotics are good for at least 15 years when stored at room temperature or lower).
For those looking for an alternative antibiotic following Doxycylines's incredible price hike, be advised that amoxicillin works just as well and is quite cheap and available in FDA-approved fish or bird doses from ebay or many vet supply companies (look for Fish Mox). Dose twice a day at 10-20 mg per pound (250 mg twice a day for a working terrier).