"The leading cause of death for healthy dogs in the United States is not car accidents or dogfighting, but instead shelter killing, the fact that, if were about disease, would be treated as an epidemic."
From page 167 of The Dog Merchants: Inside the Big Business of Breeders, Pet Stores, and Rescuers by Kim Kavin.
The ultimate cause is breeding of dogs that are unlikely to find homes. Shelter kills are mostly a sad result of this.
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